He aha te tūranga o te AI whakaputa uri i roto i te Kimi Rongoā?

He aha te tūranga o te Generative AI i roto i te Kimi Rongoā?

Whakautu poto: Ko te AI whakaputa ka tere ake te kimi rongoā wawe mā te whakaputa i ngā ngota ngota, i ngā raupapa pūmua rānei, te whakaaro i ngā huarahi hanga, me te whakaatu i ngā whakapae ka taea te whakamātautau, kia iti ake ai ngā whakamātautau "matapo" a ngā tīma. Ka tino pai te mahi ina whakatinanahia ngā herenga pakari me te whakamana i ngā putanga; ki te whakahaerehia pērā i te matakite, ka taea e ia te tinihanga me te maia.

Ngā kōrero matua hei whakaaroaro:

Whakaterenga : Whakamahia a GenAI hei whakawhānui i te whakaputa whakaaro, kātahi ka whakawhāiti mā te tātari pakari.

Ngā Here : Me whai i ngā whānuitanga o ngā āhuatanga, ngā ture tūāpapa, me ngā herenga hou i mua i te whakaputanga.

Whakamana : Whakamahia ngā putanga hei whakapae; whakaū mā te whakamahi i ngā whakamātautau me ngā tauira orthogonal.

Te Aroturuki : Ngā tohu takiuru, ngā putanga, me ngā whakamārama kia noho tonu ai ngā whakataunga hei arotake, hei arotake anō hoki.

Ātete ki te whakamahinga hē : Ārai i te turuturu me te whakawhirinaki nui mā te whakahaere, ngā mana urunga, me te arotake tangata.

He aha te tūranga o te AI whakaputa uri i roto i te Kimi Rongoā? Whakaahuatanga

Ngā tuhinga ka pai pea koe ki te pānui i muri i tēnei:

🔗 Te tūranga o te AI i roto i te hauora
Me pēhea te whakapai ake a te AI i te tautuhi mate, ngā rerengamahi, te tiaki tūroro, me ngā putanga.

🔗 Ka whakakapia rānei ngā tohunga hihi-X e te AI?
Ka tūhuratia te whakapai ake a te aunoatanga i te hihi-ā-rangi me ngā āhuatanga e noho tangata tonu ana.

🔗 Ka whakakapia ngā tākuta e te AI?
He tirohanga pono ki te pānga o te AI ki ngā mahi me ngā mahi a ngā tākuta.

🔗 Ngā taputapu taiwhanga AI pai rawa atu mō te tūhuratanga pūtaiao
Ngā taputapu taiwhanga AI tino pai hei whakateretere i ngā whakamātautau, te tātari, me te kimi.

Te tūranga o te AI whakaputa uri i roto i te Kimi Tarukino, i roto i te manawa kotahi 😮💨

Mā te AI whakaputa ka āwhina i ngā tīma rongoā ki te waihanga i ngā ngota ngota, ki te matapae i ngā āhuatanga, ki te whakaaro i ngā whakarerekētanga, ki te whakaaro i ngā huarahi hanga, ki te tūhura i ngā whakapae koiora, me te whakawhāiti i ngā huringa whakahou - inā koa i ngā kitenga tōmua me te arotautanga arataki. Nature 2023 (arotake kitenga ligand) Arotake Elsevier 2024 (tauira whakaputa i roto i te hoahoa rongoā hou)

Āe, ka taea hoki e ia te whakaputa kōrero wairangi me te maia. Koinā tetahi wāhanga o te mahi. Pērā i tētahi tauira hihiri me te mīhini rōkete. Aratohu a ngā tākuta (mōrearea moemoeā) npj Digital Medicine 2025 (anga moemoeā + anga haumaru)

He aha te hiranga o tēnei mea i tā te iwi e whakaae nei 💥

He nui ngā mahi kimi he "rapu." Rapu ātea matū, rapu koiora, rapu tuhinga, rapu hononga hanganga-mahi. Ko te raruraru he mutunga kore te ātea matū. Ngā Pūrongo Rangahau Matū 2015 (ātea matū) Irwin & Shoichet 2009 (tauine ātea matū)

Ka taea e koe te whakapau i ngā oranga maha ki te whakamātau noa i ngā rerekētanga "whaitake".

Ka hurihia e te Generative AI te reremahi mai i:

  • "Me whakamātau tātou i tā tātou e whakaaro ai"

ki:

  • "Me whakaputa he huinga kōwhiringa nui ake, atamai ake, kātahi ka whakamātau i ngā mea pai rawa atu"

Ehara i te mea mō te whakakore i ngā whakamātautau. Engari mō te whiriwhiri i ngā whakamātautau pai ake . 🧠 Nature 2023 (arotake kitenga ligand)

Waihoki, ā, kāore i te tino kōrerohia tēnei, ka āwhina i ngā tīma ki te kōrero puta noa i ngā marautanga . Ngā tohunga matū, ngā tohunga koiora, ngā tāngata DMPK, ngā kaipūtaiao rorohiko… he rerekē ngā tauira hinengaro o te katoa. Ka taea e tētahi pūnaha whakaputa uri pai te mahi hei papa tuhi tahi. Arotake o ngā Rohe i roto i te Kimihanga Rongoā 2024

He aha te mea e pai ai te putanga o te AI whakaputa mō te kimi rongoā? ✅

Kāore i te ōrite te hanganga o ngā AI whakaputa katoa. Ko te putanga "pai" mō tēnei wāhi he iti ake te aro ki ngā whakaaturanga whakahirahira, engari he nui ake te aro ki te pono kore-whakahirahira (he painga te kore-whakahirahira i konei). Nature 2023 (arotake kitenga ligand)

Ko te whakaritenga pai o te AI whakaputa uri he:

Ki te kore e taea e tō AI whakaputa te whakahaere i ngā here, he mea hanga hou noa iho. He ngahau i ngā pāti. He iti ake te ngahau i roto i te kaupapa tarukino.

Te wāhi e uru ai te AI whakaputa puta noa i te ara kimi rongoā 🧭

Anei te mahere hinengaro māmā. Ka taea e te AI whakaputa te whai wāhi ki te nuinga o ngā wāhanga, engari ka tino pai te mahi ina he nui te utu o te whakahoutanga, ā, he nui te wāhi whakapae. Nature 2023 (arotake kitenga ligand)

Ngā pā noa:

I roto i te maha o ngā kaupapa, ko ngā wikitoria nui rawa atu ka puta mai i te whakaurunga o te rerenga mahi , ehara i te mea he "mōhio" te tauira kotahi. Ko te tauira te miihini - ko te paipa te motuka. Nature 2023 (arotake kitenga ligand)

Ripanga Whakataurite: ngā huarahi rongonui o te AI whakaputa uri e whakamahia ana i roto i te kimi rongoā 📊

He tēpu kāore i tino hapa, nā te mea he āhua kāore anō kia tino hapa te ao tūturu.

Utauta / Huarahi Pai rawa atu mō (te hunga whakarongo) Te utu pea He aha i pai ai (me te wā kāore e pai ai)
Ngā kaihanga ngota ngota hou (ATAATA, kauwhata) Matū rongoā + matū whakahiato $$-$$$ He tino pai ki te tūhura tere i ngā mea hou 😎 - engari ka taea te whakaputa i ngā mea kāore i te tino pai. REINVENT 4 GENTRL (Nature Biotech 2019)
Ngā kaihanga pūmua/hanganga Ngā tīma koiora, koiora hanganga $$$ Āwhina ki te whakaaro i ngā raupapatanga me ngā hanganga - engari ko te "āhua pono" kāore i te rite ki te "mahi" AlphaFold (Nature 2021) RFdiffusion (Nature 2023)
Hoahoa ngota ngota momo horapa Ngā tīma ML matatau $$-$$$$ He kaha ki te whakarite here me te kanorau - ka taea te whakarite… he mea katoa JCIM 2024 (tauira horapa) Arotake horapa PMC 2025
Ngā pairati matapae rawa (huinga QSAR + GenAI) DMPK, ngā tīma kaupapa $$ He pai mō te whakarōpūtanga me te whakatauranga - he kino mēnā ka whakaarohia he mea kino 😬 OECD (rohe whaihua) ADMETlab 2.0
Ngā kaiwhakamahere whakamuri Matū tukatuka, CMC $$-$$$ Ka tere ake te whakaaro mō te huarahi - me whai tāngata tonu mō te whaihua me te haumaru AiZynthFinder 2020 Coley 2018 (CASP)
Ngā pairati taiwhanga maha-ara (kuputuhi + raraunga whakamātautau) Ngā tīma whakamāori $$$ He āwhina mō te kukume tohu puta noa i ngā huinga raraunga - he ngāwari ki te whakawhirinaki nui mena he pakaru ngā raraunga Nature 2024 (ngā pānga puranga i roto i te whakaahua pūtau) npj Digital Medicine 2025 (multimodal i roto i te hangarau koiora)
Ngā kaiawhina tuhinga me ngā whakapae Te katoa, i roto i te mahi $ Ka whakaiti i te wā pānui - engari ka pahekeheke ngā moemoeā, pērā i te ngaro haere o ngā tōkena. Ngā Tauira 2025 (LLM i roto i te kitenga rongoā) Aratohu a ngā rata (moemoeā)
Ngā tauira turanga ritenga ā-whare Ngā kamupene rongoā nui, ngā hangarau koiora kua putea paitia $$$$ Te mana whakahaere pai rawa atu + te whakaurunga - he utu nui hoki, he puhoi hoki te hanga (aroha mai, he pono) Arotake o Frontiers in Drug Discovery 2024

Tuhipoka: he rerekē rawa ngā utu i runga i te tauine, te rorohiko, te raihana, me te hiahia o tō rōpū ki te "monomai me te whakamahi" me te "hanga waka mokowhiti" rānei

Tirohanga tata atu: Te AI whakaputa mō te kitenga angitu me te hoahoa hou 🧩

Koinei te kaupapa matua: te whakaputa i ngā ngota ngota mai i te tīmatanga (mai i tētahi tūāpapa rānei) e ōrite ana ki tētahi kōtaha ūnga. Nature Biotechnology 2019 (GENTRL) REINVENT 4

Te āhua o tana mahi i roto i te mahi:

  1. Tautuhia ngā here

  2. Whakaputa kaitono

  3. Tātarihia kia kaha

  4. Kōwhiria he huinga iti mō te whakahiato

    • ka kōwhiri tonu te tangata, nā te mea ka hongi pea te tangata i te hongi wairangi i ētahi wā

Ko te pono whakamā: ehara i te mea ko ngā "ngota hou" anake te uara. He ngota hou e tika ana mō ngā here o tō kaupapa . Ko te wāhanga whakamutunga te mea nui. Nature 2023 (arotake kitenga ligand)

Me te whakanui rawa hoki: ina oti pai te mahi, ka rite ki te mea kua utua e koe tētahi rōpū tohunga matū taitamariki e kore e moe, e kore hoki e amuamu. Heoi anō, kāore hoki rātou e mārama he aha te moemoeā kino o tētahi rautaki tiaki motuhake, nō reira… taurite 😅.

Tirohanga tata atu: Te arotautanga o te arataki me te AI whakaputa (te whakatikatika maha-tawhā) 🎛️

Ko te arotautanga arataki te wāhi e uaua ai ngā moemoeā.

E hiahia ana koe:

  • kaha ake

  • te whiriwhiri ake

  • te pumau o te pākia

  • te wairewatanga ki runga

  • ngā tohu haumaru e heke ana

  • te uruhanga "tika tonu"

  • Ā, ka taea tonu te hanga

He arotakenga maha-whāinga matarohia tēnei. He tino pai te AI whakaputa ki te whakaaro i tētahi huinga otinga tauwhitiwhiti, kaua ki te whakaari he kotahi te matū tino tika. REINVENT 4 Elsevier 2024 (tauira whakaputa)

Ngā huarahi whai hua e whakamahia ana e ngā tīma:

  • Whakaaro ā-whakaaro : "Hangaia kia 30 ngā momo hei whakaiti i te ātete engari hei pupuri i te kaha"

  • Matawai whakakapinga : te tūhuratanga ārahi hei utu mō te tatau kaha-kaha

  • Te pekepeke o te tūāpapa : ina pā te matua ki te pakitara (te paitini, te IP, te pumau rānei)

  • Ngā whakaaro whakamārama : "Tērā pea ka āwhina tēnei rōpū porowhita i te wairewatanga engari ka pā kino ki te uruhanga" (ehara i te mea he tika i ngā wā katoa, engari he āwhina)

Kotahi te whakatūpato: ka pakarukaru pea ngā matapae āhuatanga. Mēnā kāore ō raraunga whakangungu e ōrite ki tō raupapa matū, ka hē pea te tauira. He tino hē. Ā, e kore e whakama. Ngā mātāpono whakamana QSAR a te OECD (rohe whaihua) Weaver 2008 (rohe whaihua QSAR)

Tirohanga tata atu: ADMET, paitini, me te tirotiro "kaua e whakamatea te kaupapa" 🧯

Ko te ADMET te wāhi e hinga puku ai te nuinga o ngā kaitono. Kāore te Generative AI e whakaoti i te koiora, engari ka taea e ia te whakaiti i ngā hapa ka taea te karo. ADMETlab 2.0 Waring 2015 (attrition)

Ngā tūranga noa:

  • te matapae i ngā herenga pākia (ngā wāhi o te pākia, ngā ia o te whakakorenga)

  • te tohu i ngā tohu paitini pea (ngā whakatūpato, ngā takawaenga tauhohenga hei whakakapi)

  • te whakatau tata i ngā awhe wairewa me te uruhanga

  • te whakaaro i ngā whakarerekētanga hei whakaiti i te mōrearea hERG, hei whakapai ake rānei i te pumau 🧪 FDA (ICH E14/S7B Q&A) EMA (tirohanga whānui mō te ICH E14/S7B)

Ko te tauira tino whai hua koia tēnei: ​​whakamahia a GenAI hei whakaaro i ngā kōwhiringa, engari whakamahia ngā tauira me ngā whakamātautau motuhake hei manatoko.

Ko te AI whakaputa te miihini whakatakoto whakaaro. Kei roto tonu i ngā whakamātautau te whakamana.

Tirohanga tata atu: Te AI whakaputa mō ngā mahi koiora me te hangarau pūmua 🧬✨

Ehara i te mea ko ngā ngota iti anake te kitenga rongoā. Ka whakamahia hoki te AI whakaputa mō:

He kaha te whakaputa pūmua me te raupapatanga nā te mea he tino pai te hono o te "reo" o ngā raupapatanga ki ngā tikanga ML. Engari anei te ara whakamuri noa: he pai te hono… kia kore rā anō. Nā te mea he tino kino te ārai mate, te whakapuakitanga, ngā tauira glycosylation, me ngā here whanaketanga. AlphaFold (Nature 2021) ProteinGenerator (Nat Biotech 2024)

Na, ko ngā whakaritenga pai rawa atu ko:

  • ngā tātari whanaketanga

  • te whakatau i te mōrearea o te ārai mate

  • ngā herenga hangahanga

  • ngā koropiko taiwhanga mākū mō te mahi tere 🧫

Ki te tīpokahia e koe ēnā, ka whiwhi koe i tētahi raupapa ataahua e rite ana ki tētahi diva i roto i te mahi whakaputa.

Tirohanga tata atu: Te whakamahere hanganga me ngā whakaaro hanganga whakamuri 🧰

Kei te ngokingoki puku hoki te AI whakaputa ki ngā mahi matū, ehara i te mea ko te whakaaro ngota anake.

Ka taea e ngā kaiwhakamahere whakamuri te:

  • whakaarohia ngā huarahi ki tētahi wāhi ūnga

  • whakaarohia ngā rauemi tīmatanga e wātea ana i te hokohoko

  • whakarōpūhia ngā ara mā te maha o ngā hikoinga, mā te whaihua rānei e kitea ana

  • āwhina i ngā kaimātai matū kia tere te whakakore i ngā whakaaro "ātaahua engari kāore e taea" AiZynthFinder 2020 Coley 2018 (CASP)

Ka taea e tēnei te penapena i te wā tūturu, inā koa kei te tūhura koe i ngā hanganga maha e hiahiatia ana. Heoi anō, he mea nui te tangata i konei nā te mea:

  • ngā huringa o te wātea o te matū

  • he pono ngā āwangawanga mō te haumaru me te tauine

  • he pai te āhua o ētahi mahi i runga i te pepa engari he maha ngā wā ka hē

He kupu whakarite kāore i te tino tika, engari ka whakamahia tonutia e au: te retrosynthesis He rite te AI ki te GPS e tika ana te nuinga, engari i ētahi wā ka arahi koe i roto i te roto, ā, ka tohe he ara poto. 🚗🌊 Coley 2017 (te retrosynthesis āwhina-rorohiko)

Ngā raraunga, ngā tauira maha-ara, me te mooni pōuri o ngā taiwhanga 🧾🧪

He aroha nui tō te AI whakaputa raraunga. Ka whakaputa raraunga ngā taiwhanga. I runga i te pepa, he māmā noa iho te ahua o tēnā.

Kāore.

Ko ngā raraunga taiwhanga tūturu ko:

Ka taea e ngā pūnaha whakaputa uri maha-ara te whakakotahi i:

Ina mahi, he rawe. Ka taea e koe te hura i ngā tauira kāore i te kitea, me te whakaaro i ngā whakamātautau ka ngaro pea i tētahi tohunga.

Ina kore e angitu, ka kore e angitu. Kāore e ārai i te tatau. Ka akiaki noa i a koe ki tētahi whakatau hē. Koia te take kāore e taea te whiriwhiri i te whakahaere, te whakamana, me te arotake i ngā rohe. Aratohu a ngā Tākuta Hauora (whakaaroaro) npj Rongoā Mamati 2025 (angaaroaro + anga haumaru)

Ngā tūponotanga, ngā herenga, me te wāhanga "kaua e mānumanutia e te putanga matatau" ⚠️

Ki te mea kotahi anake te mea e maumahara ana koe, kia maumahara ki tēnei: ​​he mea whakatenatena te AI whakaputa. Ka taea e ia te tangi tika, engari ka hē. Aratohu a ngā tākuta (whakaaro pōhewa)

Ngā mōrearea matua:

Ngā whakaitiiti e āwhina ana i roto i te mahi:

  • pupuri i te tangata i roto i te porowhita whakatau

  • ngā tohu me ngā putanga takiuru mō te whai i te whai

  • whakamanahia mā te whakamahi i ngā tikanga orthogonal (whakamātautau, tauira rerekē)

  • whakatinanahia ngā here me ngā tātari aunoa

  • whakaarohia ngā putanga hei whakapae, kaua hei papa pono Aratohu QSAR a te OECD

He taputapu hiko te Generative AI. Kāore ngā taputapu hiko e hanga i a koe hei kāmura… ka tere ake te hapa mena kāore koe e mōhio ki tāu mahi.

Me pēhea te whakamahi a ngā tīma i te AI whakaputa me te kore he pōrearea 🧩🛠️

He maha ngā wā ka hiahia ngā tīma ki te whakamahi i tēnei me te kore e huri i te whakahaere hei whakaaturanga pūtaiao. Koinei te āhua o te ara whakatinanatanga mahi:

Kaua hoki e whakaititia te ahurea. Ki te whakaaro ngā kaimātai matū kei te panaia rātou ki te AI, ka kore rātou e aro. Ki te penapena i te wā me te whakaute i ō rātou tohungatanga, ka tere tonu tā rātou tango. He katakata te tangata pērā 🙂.

He aha te tūranga o te AI whakaputa i roto i te Drug Discovery ina whakaitihia te aro? 🔭

Ki te whakawhāitihia, ehara te mahi i te "whakakapi i ngā kaipūtaiao". Engari ko te "whakawhānui i te whānuitanga pūtaiao." Nature 2023 (arotake kitenga ligand)

He āwhina i ngā tīma:

  • tūhuratia ētahi atu whakapae i ia wiki

  • whakaarohia ētahi atu hanganga kaitono mō ia huringa

  • te whakarite i ngā whakamātautau kia matatau ake

  • kōpeketia ngā takahuri tāruarua i waenga i te hoahoa me te whakamātautau

  • te tohatoha mātauranga puta noa i ngā wāhi motuhake Ngā Tauira 2025 (LLM i roto i te kimi rongoā)

Ā, ko te mea pea kāore i te tino arohia: ka āwhina i a koe kia kaua e moumou te auahatanga utu nui o te tangata ki ngā mahi auau. Me whakaaro te tangata ki ngā tikanga, ki ngā rautaki, me te whakamaoritanga - kaua e whakapau i ngā rā ki te hanga rārangi rerekē mā te ringa. Nature 2023 (arotake kitenga ligand)

Āe, ko te tūranga o te AI whakaputa uri i roto i te Drug Discovery he whakateretere, he whakaputa, he tātari, ā, i ētahi wā he kaiwhakararuraru. Engari he mea nui.

Whakarāpopototanga whakamutunga 🧾✅

Kei te huri te AI whakaputa hei pūmanawa matua i roto i te kimi rongoā hou nā te mea ka taea e ia te whakaputa i ngā ngota, ngā whakapae, ngā raupapatanga, me ngā huarahi tere atu i te tangata - ā, ka taea e ia te āwhina i ngā tīma ki te whiriwhiri i ngā whakamātautau pai ake. Arotake o Frontiers in Drug Discovery 2024 Nature 2023 (arotake kitenga ligand)

Ngā tohu whakarāpopototanga:

Ki te whakaarohia e koe he hoa mahi - ehara i te matakite - ka taea e ia te neke whakamua i ngā kaupapa. Ā, ki te whakaarohia e koe he matakite ... āe, tera pea ka whai anō koe i taua GPS ki roto i te roto. 🚗🌊

Ngā Pātai Auau

He aha te tūranga o te AI whakaputa uri i roto i te kimi rongoā?

Ko te AI whakaputa tuatahi ka whānui ake i te ara whakaaro i roto i te kitenga wawe me te arotautanga ārahi mā te whakaaro i ngā ngota ngota kaitono, ngā raupapa pūmua, ngā huarahi hanga, me ngā whakapae koiora. Ko te uara he iti ake te "whakakapi i ngā whakamātautau" engari he nui ake te "whiriwhiri i ngā whakamātautau pai ake" mā te whakaputa i ngā kōwhiringa maha, kātahi ka tātari kaha. He pai ake te mahi hei whakatere i roto i tētahi rerenga mahi whakahaere, kaua hei kaiwhakatau takitahi.

Kei hea te mahi tino pai a te AI whakaputa puta noa i te ara rapu rongoā?

Ko te tikanga, ka puta te uara nui rawa atu i te wā e whānui ana te wāhi whakapae, ā, he nui te utu mō te whakatikatika, pērā i te tautuhi i ngā pānga, te hoahoa hou, me te arotau i ngā arataki. Ka whakamahia hoki e ngā tīma mō te whakarōpūtanga ADMET, ngā whakaaro whakamuri, me te tautoko tuhinga, whakapae rānei. Ko ngā hua nui rawa atu ka puta mai i te whakauru i te whakaputa me ngā tātari, te kaute, me te arotake tangata, kaua ki te tumanako kia "atamai" tētahi tauira kotahi

Me pēhea te whakatakoto here kia kore ai ngā tauira whakaputa uri e whakaputa i ngā ngota koretake?

Ko tētahi huarahi mahi ko te tautuhi i ngā here i mua i te whakaputanga: ngā awhe āhuatanga (pēnei i te wairewatanga, ngā whāinga logP rānei), ngā ture hanganga papa, ngā āhuatanga pae here, me ngā here hou. Kātahi ka whakatinanahia ngā tātari matū rongoā (tae atu ki ngā rōpū PAINS/tauhohe) me ngā arowhai āheinga whakahiato. He tino āwhina te whakaputanga here-tuatahi ki te hoahoa ngota ngota momo horapa me ngā anga pēnei i a REINVENT 4, ka taea te whakakōwae i ngā whāinga maha-whāinga.

Me pēhea te whakamana a ngā tīma i ngā putanga GenAI kia kore ai e moemoeā noa me te tino whakapono ki a rātou anō?

Me whakaaro ki ia putanga hei whakapae, kaua hei whakatau, ā, me whakamana mā te whakamahi i ngā whakamātautau me ngā tauira orthogonal. Honoa te whakaputanga ki te tātari kaha, te taunga, te kaute rānei i ngā wā e tika ana, me ngā tirotiro rohe-whakamahinga mō ngā matapae momo-QSAR. Me whakaatu te koretake ina taea, nā te mea ka taea e ngā tauira te hē māia i runga i te matū i waho o te tohatoha, i ngā kereme koiora wiri rānei. Ko te arotake tangata-i-roto-i-te-porowhita tonu te āhuatanga haumaru matua.

Me pēhea te ārai i te turuturu raraunga, te mōrearea IP, me ngā putanga "kua maumaharatia"?

Whakamahia ngā mana whakahaere me ngā mana uru kia kore ai ngā taipitopito kaupapa tairongo e whakaurua noa ki roto i ngā tohu, me te takiuru i ngā tohu/putanga kia taea ai te arotake. Whakaūhia ngā arowhai hou me te ōrite kia kore ai ngā kaitono kua hangaia e noho tata rawa ki ngā matū e mōhiotia ana, ki ngā rohe tiaki rānei. Kia mārama ngā ture mō ngā raraunga e whakaaetia ana i roto i ngā pūnaha o waho, ā, kia pai ake ngā taiao whakahaere mō ngā mahi tairongo nui. Mā te arotake tangata ka taea te hopu wawe i ngā whakaaro "tino mōhiotia".

Me pēhea te whakamahi i te AI whakaputa mō te arotautanga arahi me te whakatikatika i ngā tawhā maha?

I roto i te arotautanga arataki, he mea nui te AI whakaputa uri nā te mea ka taea e ia te whakatakoto i ngā otinga tauwhitinga maha, kaua ki te whai i tētahi matū "tino pai" kotahi. Ko ngā rerengamahi noa ko te whakaaro anaro, te matawai i ngā whakakapinga ārahi, me te pekepeke tūāpapa ina aukatihia te ahunga whakamua e ngā here kaha, paitini, IP rānei. Ka pakarukaru pea ngā matapae āhuatanga, nō reira ka whakarōpūhia e ngā tīma ngā kaitono me ngā tauira maha, kātahi ka whakaū i ngā kōwhiringa pai rawa atu mā te whakamātautau.

Ka taea e te AI whakaputa uri te āwhina i ngā mahi koiora me te hangarau pūmua?

Ae - ka whakamahia e ngā tīma mō te whakaputa raupapatanga paturopi, ngā whakaaro mō te pakeketanga o te hononga, te whakapai ake i te pumau, me te tūhuratanga whākōkī, peptide rānei. Tērā pea ka kitea he mea tika te whakaputa pūmua/raupapatanga engari kāore e taea te whakawhanake, nō reira he mea nui kia whakamahia ngā tātari whanaketanga, te ārai mate, me te āheinga hanga. Ka taea e ngā taputapu hanganga pērā i a AlphaFold te tautoko i te whakaaro, engari kāore tonu te "hanganga whaitake" e whakaatu ana i te whakaaturanga, te mahi, te haumaru rānei. He mea nui tonu ngā koropiko taiwhanga-makuku.

Me pēhea te tautoko a te AI whakaputa i te whakamahere whakahiato me te whakahiatotanga whakamuri?

Ka taea e ngā kaiwhakamahere whakamuri te whakaaro i ngā huarahi, ngā rauemi tīmatanga, me ngā whakatauranga huarahi hei tere ake i te whakaaro me te whakakore wawe i ngā ara kāore e taea. Ko ngā taputapu me ngā huarahi pēnei i te whakamahere ā-AiZynthFinder he tino whai hua ina honoa ki ngā tirotiro whaihua o te ao tūturu mai i ngā kaimātai matū. Ko te wātea, te haumaru, ngā here tauine, me ngā "tauhohenga pepa" e kore e angitu i roto i te mahi me whai whakaaro tangata tonu. Mā te whakamahi i tēnei ara, ka penapena i te wā me te kore e whakaaro kua ea te matū.

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